{"id":129,"date":"2021-07-08T19:41:15","date_gmt":"2021-07-08T19:41:15","guid":{"rendered":"http:\/\/themenectar.com\/demo\/salient-wellness\/?p=129"},"modified":"2026-03-02T10:54:11","modified_gmt":"2026-03-02T15:54:11","slug":"oncogene-testing","status":"publish","type":"post","link":"https:\/\/happylungsproject.org\/oncogene-testing\/","title":{"rendered":"Oncogene Testing: What it is and Why it is Important"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_spacing=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text]<a href=\"https:\/\/www.cancer.org\" target=\"_blank\" rel=\"noopener\">Cancers<\/a> can be caused by many individual or combined factors including but not limited to: environmental, genetic and mutations. In this piece, we will focus on genetic mutations which cause the growth or proliferation of cells potentially resulting in the formation of malignant tumors.<span class=\"Apple-converted-space\">\u00a0 <\/span>A diagnosis of nonsmall cell lung cancer is just the beginning in understanding the disease, its origin and optimal treatments.<span class=\"Apple-converted-space\">\u00a0 <\/span>After the general diagnosis of NSCLC, the patient can seek information as to whether the cancer was caused by genetic mutation including BRAF mutations, HER2 insertions, PIK3CA mutations, FGFR1 amplifications, DDR2 mutations, ROS1 rearrangements, and RET rearrangements.<span class=\"Apple-converted-space\">\u00a0 <\/span>With the testing and confirmatory diagnosis, then oncologists can target the genetic mutations with specific treatment.<span class=\"Apple-converted-space\">\u00a0 <\/span>For example, if cancer is caused by RET mutation, then the patient may receive selpercatnib or Retevmo which is a first generation RET inhibitor designed to interfere with cancer cell proliferation.<span class=\"Apple-converted-space\">\u00a0 <\/span>The RET inhibitor is the best hope to stop the progression of the disease caused by genetic mutation.<span class=\"Apple-converted-space\">\u00a0 <\/span>However, without the oncogene testing, this treatment would not be available as the specific genetic mutation must be diagnosed first.<span class=\"Apple-converted-space\">\u00a0 <\/span>Genetic testing is the gateway to optimal treatment and a healthier future. <span class=\"Apple-converted-space\">\u00a0<\/span>\r\n\r\nFor more information about testing and treatment:\r\n\r\n<a href=\"https:\/\/www.mayocliniclabs.com\/test-catalog\/Overview\/35539\" target=\"_blank\" rel=\"noopener\">https:\/\/www.mayocliniclabs.com\/test-catalog\/Overview\/35539<\/a>\r\n\r\n<a href=\"https:\/\/www.retevmo.com\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.retevmo.com\/<\/a>\r\n\r\n&nbsp;\r\n\r\n[\/vc_column_text][\/vc_column][\/vc_row]<!-- \/wp:post-content -->","protected":false},"excerpt":{"rendered":"<p>[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_spacing=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221;&#8230;<\/p>\n","protected":false},"author":15,"featured_media":299,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[],"class_list":{"0":"post-129","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-research"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Oncogene Testing: What it is and Why it is Important - The Happy Lungs Project<\/title>\n<meta name=\"description\" content=\"Cancers can be caused by many individual or combined factors including but not limited to: environmental, genetic and mutations. 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